FSLLRY-NH2 TFA

• CAT Number: I045804
• Molecular Formula: C41H61F3N10O10
• Molecular Weight: 910.98
• Purity: ≥95%
• IUPAC Name: (2S)-N-[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanamide;2,2,2-trifluoroacetic acid
• InChI: InChI=1S/C39H60N10O8.C2HF3O2/c1-22(2)17-30(36(55)45-28(11-8-16-44-39(42)43)35(54)46-29(33(41)52)20-25-12-14-26(51)15-13-25)47-37(56)31(18-23(3)4)48-38(57)32(21-50)49-34(53)27(40)19-24-9-6-5-7-10-24;3-2(4,5)1(6)7/h5-7,9-10,12-15,22-23,27-32,50-51H,8,11,16-21,40H2,1-4H3,(H2,41,52)(H,45,55)(H,46,54)(H,47,56)(H,48,57)(H,49,53)(H4,42,43,44);(H,6,7)/t27-,28-,29-,30-,31-,32-;/m0./s1
• InChIKey: YOHKVKBYKRRTME-YQWGHBPESA-N
• SMILES: CC(C)C[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CC2=CC=CC=C2)N.C(=O)(C(F)(F)F)O

FSLLRY-NH₂ TFA（Cat No.:I045804）is the trifluoroacetate salt of the synthetic hexapeptide FSLLRY, amidated at the C-terminus to enhance stability and receptor affinity. This peptide functions as a selective antagonist of the PAR1 (protease-activated receptor-1), a receptor activated by thrombin and involved in platelet aggregation, vascular function, and inflammation. By blocking PAR1 signaling, FSLLRY-NH₂ TFA is widely used in cardiovascular and hematology research to study thrombotic mechanisms, endothelial responses, and inflammatory pathways. Its defined structure and stability make it a valuable tool in receptor pharmacology and therapeutic exploration.