FT113

• CAT Number: I019503
• CAS Number: 1630808-89-7
• Molecular Formula: C₂₂H₂₀FN₃O₄
• Molecular Weight: 409.41
• Purity: ≥95%
• Target: Fatty Acid Synthase (FASN)

FT113 (CAT: I019503) is a potent and orally active inhibitor of fatty acid synthase (FASN), an enzyme crucial for de novo fatty acid synthesis. By inhibiting FASN, FT113 disrupts the production of fatty acids, which are essential for cell growth and proliferation, particularly in cancer cells. This inhibition can lead to impaired tumor cell survival and growth. FT113’s unique mechanism of action makes it a promising candidate for the development of novel anti-cancer therapies aimed at targeting the metabolic vulnerabilities of cancer cells.

Reference

[1]. Martin MW, et al. Discovery and optimization of novel piperazines as potent inhibitors of fatty acid synthase (FASN). Bioorg Med Chem Lett. 2019 Apr 15;29(8):1001-1006.