Fumonisin B1

• CAT Number: R049027
• CAS Number: 116355-83-0
• Molecular Formula: C34H59NO15
• Molecular Weight: 721.8
• Purity: ≥95%
• Synonyms: (2R,2’R)-1,2,3-Propanetricarboxylic Acid 1,1’-[(1S,2R)-1-[(2S,4R,9R,11S,12S)-12-Amino-4,9,11-trihydroxy-2-methyltridecyl]-2-[(1R)-1-methylpentyl]-1,2-ethanediyl] Ester; Macrofusine
• Target: Protein Ser/Thr Phosphatases
• Solubility: Limited solubility
• Storage: Store at 4°C
• InChIKey: UVBUBMSSQKOIBE-CPRNOWDYSA-N
• SMILES: C[C@H](N)[C@@H](O)C[C@H](O)CCCC[C@@H](O)C[C@H](C)C[C@H](OC(C[C@H](C(O)=O)CC(O)=O)=O)[C@H](OC(C[C@H](C(O)=O)CC(O)=O)=O)[C@H](C)CCCC

Fumonisin B1 is a mycotoxin produced by fungi of the genus Fusarium, commonly found in maize and other cereals. It is known for its potent toxicity in animals and its association with various health issues in humans, including esophageal cancer and neural tube defects. Fumonisin B1 disrupts sphingolipid metabolism by inhibiting ceramide synthase, leading to the accumulation of toxic intermediates. This disruption can cause cell dysfunction, increased oxidative stress, and apoptosis. As a result, Fumonisin B1 is a significant concern in food safety and agricultural industries, necessitating monitoring and control to prevent contamination of food supplies.