Furanone C-30

• CAT Number: I015156
• CAS Number: 247167-54-0
• Molecular Formula: C5H2Br2O2
• Molecular Weight: 253.88
• Purity: ≥95%
• Synonyms: (5Z)-4-bromo-5-(bromomethylidene)furan-2-one
• InChI: InChI=1S/C5H2Br2O2/c6-2-4-3(7)1-5(8)9-4/h1-2H/b4-2-
• InChIKey: DPGLBHQUHFJRJS-RQOWECAXSA-N
• SMILES: C1=C(C(=CBr)OC1=O)Br

Furanone C-30 is a quorum sensing inhibitor. Furanone C-30 can effectively inhibit bacterial biofilm formation by S. mutans and its luxSmutant strain[1].
The difference in the OD590 values is statistically significant at concentrations of 2.0 μg/mL and 4.0 μg/mL compared with the control group. Furanone C-30 (2.0 μg/mL and 4.0 μg/mL) can inhibit biofilm formation by S. mutans and its luxS mutant strain, although it does not affect the bacterial growth rate itself[1].

Reference

[1]. Zhiyan He, et al. Use of the quorum sensing inhibitor furanone C-30 to interfere with biofilm formation by Streptococcus mutans and its luxS mutant strain. Int J Antimicrob Agents. 2012 Jul;40(1):30-5.
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