For research use only. Not for therapeutic Use.
Furosemide is a potent loop diuretic widely used to treat conditions such as edema associated with heart failure, liver disease, and kidney disorders, as well as hypertension. By inhibiting the sodium-potassium-chloride co-transporter in the thick ascending limb of the loop of Henle, Furosemide prevents sodium and chloride reabsorption, leading to increased urine output and reduced fluid retention. It is known for its rapid action and effectiveness in managing fluid overload. Furosemide is also used in some cases to treat hypercalcemia by promoting calcium excretion. Its versatility makes it a key medication in cardiovascular and renal treatment protocols.
Catalog Number | A000323 |
CAS Number | 54-31-9 |
Synonyms | Frusemide; 54-31-9; Lasix; Furosemid; Furanthril |
Molecular Formula | C12H11ClN2O5S |
Purity | ≥95% |
Target | Neuronal Signaling |
Solubility | >14.9mg/mL in DMSO |
Storage | -20°C |
InChI | 1S/C12H11ClN2O5S/c13-9-5-10(15-6-7-2-1-3-20-7)8(12(16)17)4-11(9)21(14,18)19/h1-5,15H,6H2,(H,16,17)(H2,14,18,19) |
InChIKey | ZZUFCTLCJUWOSV-UHFFFAOYSA-N |
SMILES | C1=COC(=C1)CNC2=CC(=C(C=C2C(=O)O)S(=O)(=O)N)Cl |