For research use only. Not for therapeutic Use.
Fusicoccin（Cat No.:I014998）is a diterpene glucoside phytotoxin produced by the fungus Fusicoccum amygdali, best known for its strong plant physiological effects. It irreversibly activates plasma membrane H⁺-ATPases by stabilizing their interaction with 14-3-3 proteins, leading to enhanced proton efflux, cell wall acidification, and stomatal opening. This action disrupts normal water balance and growth regulation, making it a valuable tool in plant physiology research. Beyond botany, fusicoccin has attracted interest in chemical biology and drug discovery as a molecular probe for studying protein–protein interactions, signaling pathways, and potential therapeutic applications.
| CAS Number | 20108-30-9 |
| Synonyms | [(2S)-2-[(1E,3R,4S,8R,9R,10R,11S,14S)-8-[(2S,3R,4S,5R,6R)-4-acetyloxy-3,5-dihydroxy-6-(2-methylbut-3-en-2-yloxymethyl)oxan-2-yl]oxy-4,9-dihydroxy-14-(methoxymethyl)-3,10-dimethyl-6-tricyclo[9.3.0.03,7]tetradeca-1,6-dienyl]propyl] acetate |
| Molecular Formula | C36H56O12 |
| Purity | ≥95% |
| IUPAC Name | [(2S)-2-[(1E,3R,4S,8R,9R,10R,11S,14S)-8-[(2S,3R,4S,5R,6R)-4-acetyloxy-3,5-dihydroxy-6-(2-methylbut-3-en-2-yloxymethyl)oxan-2-yl]oxy-4,9-dihydroxy-14-(methoxymethyl)-3,10-dimethyl-6-tricyclo[9.3.0.03,7]tetradeca-1,6-dienyl]propyl] acetate |
| InChI | InChI=1S/C36H56O12/c1-10-35(6,7)45-17-26-30(41)33(46-21(5)38)31(42)34(47-26)48-32-28-24(18(2)15-44-20(4)37)13-27(39)36(28,8)14-25-22(16-43-9)11-12-23(25)19(3)29(32)40/h10,14,18-19,22-23,26-27,29-34,39-42H,1,11-13,15-17H2,2-9H3/b25-14-/t18-,19-,22-,23+,26-,27+,29-,30-,31-,32-,33+,34-,36+/m1/s1 |
| InChIKey | KXTYBXCEQOANSX-WYKQKOHHSA-N |
| SMILES | C[C@@H]1[C@@H]\2CC[C@@H](/C2=C/[C@]3([C@H](CC(=C3[C@H]([C@@H]1O)O[C@@H]4[C@@H]([C@H]([C@@H]([C@H](O4)COC(C)(C)C=C)O)OC(=O)C)O)[C@H](C)COC(=O)C)O)C)COC |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
