For research use only. Not for therapeutic Use.
FX12 is a selective inhibitor and degrader of RNF5 E3 ubiquitin ligase. FX12 binds directly to RNF5 and inhibits its E3 activity in vitro as well as promoting proteasomal degradation of RNF5 in cells via ERAD. KEYWORDS: FX12 | Supplier | RNF5 inhibitor/degrader | FX-12 | FX 12 | CAS [1807639-36-6] | Protein degradation | Ubiquitin Ligase (E3; other) | Inhibitor | Degrader | Enzymes | Chemical biology tool
| Catalog Number | I047723 |
| CAS Number | 1807639-36-6 |
| Molecular Formula | C10H8O4S |
| Purity | ≥95% |
| Reference | J Ruan et al. A small-molecule inhibitor and degrader of the RNF5 ubiquitin ligase. Mol Biol Cell. 2022 Nov 1;33(13):ar120. |
