G-Protein antagonist peptide TFA

• CAT Number: I045858
• Molecular Formula: C59H65F3N12O11S
• Molecular Weight: 1207.28
• Purity: ≥95%

G-Protein antagonist peptide TFA is a truncated substance P-related peptide, competes with receptor for G protein binding. G-Protein antagonist peptide TFA inhibits the activation of Gi or Go by M2 muscarinic cholinergic receptor (M2 mAChR) or of Gs by beta-adrenergic receptor in the reconstituted phospholipid vesicles, assayed by receptor-promoted GTP hydrolysis[1].

Reference

[1]. Mukai H, et al. G protein antagonists. A novel hydrophobic peptide competes with receptor for G protein binding. J Biol Chem. 1992;267(23):16237-16243.
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