For research use only. Not for therapeutic Use.
G1023 is a potent, selective, and brain-penetrant inhibitor of leucine-rich repeat kinase 2 (LRRK2).
Catalog Number | I027868 |
Synonyms | G1023; G-1023; G 1023 |
Molecular Formula | C18H19F4N5O3 |
Purity | 98% |
Solubility | Soluble in DMSO |
Appearance | Solid powder |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
IUPAC Name | [4-(4-Methylamino-5-trifluoromethyl-pyrimidin-2-ylamino)-2-fluoro-5-methoxy-phenyl]-morpholin-4-yl-methanone |
InChI | InChI=1S/C18H19F4N5O3/c1-23-15-11(18(20,21)22)9-24-17(26-15)25-13-8-12(19)10(7-14(13)29-2)16(28)27-3-5-30-6-4-27/h7-9H,3-6H2,1-2H3,(H2,23,24,25,26) |
InChIKey | XRGIIJXYVHEZPX-UHFFFAOYSA-N |
SMILES | O=C(C1=CC(OC)=C(NC2=NC=C(C(F)(F)F)C(NC)=N2)C=C1F)N3CCOCC3 |