For research use only. Not for therapeutic Use.
G244-LM is a potent and specific inhibitor of tankyrase 1/2 that inhibits Wnt signaling[1].
| Catalog Number | R067042 |
| CAS Number | 1563007-08-8 |
| Synonyms | 2-[4-(2-methylsulfonylphenyl)piperazin-1-yl]-3,5,7,8-tetrahydrothiopyrano[4,3-d]pyrimidin-4-one |
| Molecular Formula | C18H22N4O3S2 |
| Purity | ≥95% |
| InChI | InChI=1S/C18H22N4O3S2/c1-27(24,25)16-5-3-2-4-15(16)21-7-9-22(10-8-21)18-19-14-6-11-26-12-13(14)17(23)20-18/h2-5H,6-12H2,1H3,(H,19,20,23) |
| InChIKey | JSQPAEVPPSCQMV-UHFFFAOYSA-N |
| SMILES | CS(=O)(=O)C1=CC=CC=C1N2CCN(CC2)C3=NC4=C(CSCC4)C(=O)N3 |
| Reference | [1]. Lau T, et al. A novel tankyrase small-molecule inhibitor suppresses APC mutation-driven colorectal tumor growth. Cancer Res. 2013 May 15;73(10):3132-44. |
