GAC0001E5

• CAT Number: I027899
• CAS Number: 927969-67-3
• Molecular Formula: C17H12F3N3O
• Molecular Weight: 331.29
• Purity: ≥95%
• Synonyms: 4-phenyl-2-[3-(trifluoromethyl)anilino]-1H-pyrimidin-6-one
• InChI: InChI=1S/C17H12F3N3O/c18-17(19,20)12-7-4-8-13(9-12)21-16-22-14(10-15(24)23-16)11-5-2-1-3-6-11/h1-10H,(H2,21,22,23,24)
• InChIKey: NKINUPRRPNHKNN-UHFFFAOYSA-N
• SMILES: C1=CC=C(C=C1)C2=CC(=O)NC(=N2)NC3=CC=CC(=C3)C(F)(F)F

GAC0001E5 (Cat No.: I027899) is a small-molecule compound under investigation for its potential therapeutic applications in oncology. It is designed to target specific signaling pathways involved in cancer cell survival, proliferation, and metastasis. While the exact mechanism of action is still being studied, GAC0001E5 is believed to modulate key enzymes or receptors that drive tumor progression. Preclinical research is focused on evaluating its efficacy and safety, with the goal of positioning GAC0001E5 as a novel treatment for various solid and hematologic cancers.

Reference

[1]. Karaboga H, et al. Screening of Focused Compound Library Targeting Liver X Receptors in Pancreatic Cancer Identified Ligands with Inverse Agonist and Degrader Activity. ACS Chem Biol. 2020 Nov 20;15(11):2916-2928.
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