For research use only. Not for therapeutic Use.
GAC0001E5 is an LXR inverse agonist. GAC0001E5 has antiproliferative activity and can be used in cancer research[1].
| Catalog Number | I027899 |
| CAS Number | 927969-67-3 |
| Synonyms | 4-phenyl-2-[3-(trifluoromethyl)anilino]-1H-pyrimidin-6-one |
| Molecular Formula | C17H12F3N3O |
| Purity | ≥95% |
| InChI | InChI=1S/C17H12F3N3O/c18-17(19,20)12-7-4-8-13(9-12)21-16-22-14(10-15(24)23-16)11-5-2-1-3-6-11/h1-10H,(H2,21,22,23,24) |
| InChIKey | NKINUPRRPNHKNN-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C=C1)C2=CC(=O)NC(=N2)NC3=CC=CC(=C3)C(F)(F)F |
| Reference | [1]. Karaboga H, et al. Screening of Focused Compound Library Targeting Liver X Receptors in Pancreatic Cancer Identified Ligands with Inverse Agonist and Degrader Activity. ACS Chem Biol. 2020 Nov 20;15(11):2916-2928. |
