Galacto-PUGNAc

• CAT Number: R054786
• CAS Number: 1145878-98-3
• Molecular Formula: C15H19N3O7
• Molecular Weight: 353.331
• Purity: ≥95%
• Synonyms: 2-(Acetylamino)-2-deoxy-N-[[(phenylamino)carbonyl]oxy]-D-galactonimidic Acid δ-Lactone; Gal-PUGNAc
• Storage: -20°C
• IUPAC Name: [(Z)-[(4R,5R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-ylidene]amino] N-phenylcarbamate
• InChI: InChI=1S/C15H19N3O7/c1-8(20)16-11-13(22)12(21)10(7-19)24-14(11)18-25-15(23)17-9-5-3-2-4-6-9/h2-6,10-13,19,21-22H,7H2,1H3,(H,16,20)(H,17,23)/b18-14-/t10,11,12-,13+/m0/s1
• InChIKey: PBLNJFVQMUMOJY-AYYVYFISSA-N
• SMILES: CC(=O)NC1C(C(C(OC1=NOC(=O)NC2=CC=CC=C2)CO)O)O

Galacto-PUGNAc is a synthetic glycosylation inhibitor used in chemical biology research to study glycosidase enzymes and carbohydrate processing. It is designed to selectively inhibit O-GlcNAcase, an enzyme involved in O-GlcNAcylation, a post-translational modification in cells. Galacto-PUGNAc mimics the natural substrate of O-GlcNAcase, interfering with its activity and allowing researchers to investigate the role of O-GlcNAcylation in cellular processes. This compound has potential applications in understanding glycosylation-related diseases and developing therapeutic strategies targeting glycosidase enzymes.