Galangin

• CAT Number: I004028
• CAS Number: 548-83-4
• Molecular Formula: C15H10O5
• Molecular Weight: 270.24
• Purity: ≥95%
• Synonyms: NSC 407229;3,5,7-Trihydroxyflavone
• Solubility: 10 mM in DMSO
• Storage: -20°C
• IUPAC Name: 3,5,7-trihydroxy-2-phenylchromen-4-one
• InChI: InChI=1S/C15H10O5/c16-9-6-10(17)12-11(7-9)20-15(14(19)13(12)18)8-4-2-1-3-5-8/h1-7,16-17,19H
• InChIKey: VCCRNZQBSJXYJD-UHFFFAOYSA-N
• SMILES: C1=CC=C(C=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O

Galangin（Cat No.:I004028）is a natural flavonoid found in high concentrations in Alpinia officinarum (galangal) and propolis. Known for its antioxidant, anti-inflammatory, and antimicrobial properties, Galangin has garnered attention in pharmacological research. It exhibits potential as an anti-cancer agent by inducing apoptosis and inhibiting cell proliferation in various cancer cell lines. Additionally, Galangin supports cardiovascular health by reducing oxidative stress and modulating lipid levels. Its diverse bioactivities make Galangin a valuable compound in exploring natural therapies for chronic inflammation, infection control, and cancer prevention.

Reference

[1]. Ciolino HP, et al. The flavonoid galangin is an inhibitor of CYP1A1 activity and an agonist/antagonist of the aryl hydrocarbon receptor. Br J Cancer. 1999 Mar;79(9-10):1340-6.

[2]. Wen M, et al. Galangin induces autophagy through upregulation of p53 in HepG2 cells. Pharmacology. 2012;89(5-6):247-55.

[3]. Lu YH, et al. Mechanism and inhibitory effect of galangin and its flavonoid mixture from Alpinia officinarum on mushroom tyrosinase and B16 murine melanoma cells. J Enzyme Inhib Med Chem. 2007 Aug;22(4):433-8.