Galanthamine-O-(methyl-d3)-N-(methyl-d3)

• CAT Number: R009216
• CAS Number: 1128109-00-1
• Molecular Formula: C17H21NO3
• Molecular Weight: 293.396
• Purity: ≥95%
• Synonyms: (4aS,6R,8aS)-4a,5,9,10,11,12-Hexahydro-3-(methoxy-d3)-11-(methyl-d3)-6H-benzofurol[3a,3,2,-ef][2]benzazepin-6-ol; BRN 0093736-d6; Galantamin-d6; Galantamina-d6; Galantamine-d6; (-)-Galanthamine-d6; Jilkon-d6; Lycoremin-d6; Lycoremine-d6; NSC 100058-d
• Target: Apoptosis
• Storage: -20°C
• IUPAC Name: (1S,12S,14R)-9-(trideuteriomethoxy)-4-(trideuteriomethyl)-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraen-14-ol
• InChI: InChI=1S/C17H21NO3/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17/h3-6,12,14,19H,7-10H2,1-2H3/t12-,14-,17-/m0/s1/i1D3,2D3
• InChIKey: ASUTZQLVASHGKV-BQBSLYESSA-N
• SMILES: [2H]C([2H])([2H])N1CC[C@@]23C=C[C@@H](C[C@@H]2OC4=C(C=CC(=C34)C1)OC([2H])([2H])[2H])O

Galanthamine-O-(methyl-d3)-N-(methyl-d3)(CAT: R009216) is a deuterium-labeled derivative of galanthamine, an alkaloid found in various plants, including snowdrops and daffodils. Its mode of action involves being a labeled form of galanthamine, a cholinesterase inhibitor that is used in the treatment of Alzheimer’s disease and other cognitive disorders. Pharmacologically, Galanthamine-O-(methyl-d3)-N-(methyl-d3) is not used as a therapeutic drug on its own. Instead, it serves as a labeled internal standard in analytical chemistry and bioanalytical studies. By using deuterium-labeled compounds like Galanthamine-O-(methyl-d3)-N-(methyl-d3) as internal standards, researchers can accurately quantify and identify galanthamine and related compounds in complex samples using various analytical techniques, such as mass spectrometry.