For research use only. Not for therapeutic Use.
Galectin-3-IN-1 (Compound 1) is a potent multivalent inhibitor of galectin-3 (Gal-3). Galectin-3 participates in many cancer-related metabolic processes[1]. Galectin-3-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
| Catalog Number | I043894 |
| CAS Number | 1989627-40-8 |
| Synonyms | (2S,3R,4S,5S,6R)-2-[(2S,3R,4S,5S,6R)-3,5-dihydroxy-6-(hydroxymethyl)-4-prop-2-ynoxyoxan-2-yl]sulfanyl-6-(hydroxymethyl)-4-prop-2-ynoxyoxane-3,5-diol |
| Molecular Formula | C18H26O10S |
| Purity | ≥95% |
| InChI | InChI=1S/C18H26O10S/c1-3-5-25-15-11(21)9(7-19)27-17(13(15)23)29-18-14(24)16(26-6-4-2)12(22)10(8-20)28-18/h1-2,9-24H,5-8H2/t9-,10-,11+,12+,13-,14-,15+,16+,17+,18+/m1/s1 |
| InChIKey | XBXOXPJSVPXLNY-USCYINILSA-N |
| SMILES | C#CCOC1C(C(OC(C1O)SC2C(C(C(C(O2)CO)O)OCC#C)O)CO)O |
| Reference | [1]. David Vrbata, et al. Glycopolymers Decorated with 3- O-Substituted Thiodigalactosides as Potent Multivalent Inhibitors of Galectin-3. J Med Chem. 2022 Mar 10;65(5):3866-3878. |
