Gallein

• CAT Number: I010697
• CAS Number: 2103-64-2
• Molecular Formula: C20H12O7
• Molecular Weight: 364.31
• Purity: ≥95%
• Synonyms: 3/’,4/’,5/’,6/’-Tetrahydroxyspiro[isobenzofuran-1(3H),9/’-(9H)xanthen]-3-one
• Target: PI3K
• Solubility: Soluble to 75 mM in DMSO and to 10 mM in ethanol
• Storage: Room Temperature
• IUPAC Name: 3/',4/',5/',6/'-tetrahydroxyspiro[2-benzofuran-3,9/'-xanthene]-1-one
• InChI: InChI=1S/C20H12O7/c21-13-7-5-11-17(15(13)23)26-18-12(6-8-14(22)16(18)24)20(11)10-4-2-1-3-9(10)19(25)27-20/h1-8,21-24H
• InChIKey: PHLYOKFVXIVOJC-UHFFFAOYSA-N
• SMILES: C1=CC=C2C(=C1)C(=O)OC23C4=C(C(=C(C=C4)O)O)OC5=C3C=CC(=C5O)O

Gallein（Cat No.:I010697） is a compound that functions as an inhibitor of G protein βγ (Gβγ) subunit signaling. It disrupts the interaction between Gβγ subunits and PI3Kγ, a signaling protein involved in cell growth and survival. Due to its ability to inhibit Gβγ signaling, gallein exhibits antitumor activity, making it a potential candidate for cancer treatment. Interestingly, gallein also finds application as a red dye, an acid-base indicator, and a detection reagent for phosphate in various laboratory settings.