For research use only. Not for therapeutic Use.
Gallopamil, (-)-（Cat No.:I027916）is a calcium channel blocker primarily used to treat cardiovascular conditions such as hypertension and angina. It selectively inhibits L-type calcium channels, reducing calcium influx into smooth muscle cells and cardiac myocytes, leading to vasodilation and decreased heart rate. This mechanism helps to lower blood pressure and improve blood flow to the heart, reducing the workload on the heart. Gallopamil, (-)- has been studied for its antiarrhythmic properties as well. Research into its long-term safety and efficacy continues, especially in comparison to other calcium channel blockers.
| CAS Number | 36622-40-9 |
| Synonyms | Gallopamil, (-)-; (-)-Gallopamil; (-)-D 600; (-)-Methoxyverapamil; (S)-Gallopamil; |
| Molecular Formula | C28H40N2O5 |
| Purity | 98% |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | (2S)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-yl-2-(3,4,5-trimethoxyphenyl)pentanenitrile |
| InChI | InChI=1S/C28H40N2O5/c1-20(2)28(19-29,22-17-25(33-6)27(35-8)26(18-22)34-7)13-9-14-30(3)15-12-21-10-11-23(31-4)24(16-21)32-5/h10-11,16-18,20H,9,12-15H2,1-8H3/t28-/m0/s1 |
| InChIKey | XQLWNAFCTODIRK-NDEPHWFRSA-N |
| SMILES | CC(C)[C@](CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C(=C2)OC)OC)OC |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
