GalNAc unconjugated/naked Fitusiran sodium

For research use only. Not for therapeutic Use.

  • CAT Number: I041222
  • Molecular Weight: 14459.60
  • Purity: ≥95%
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GalNAc unconjugated/naked Fitusiran (sodium), an small interfering RNA without GalNAc conjugation, specifically targets antithrombin (AT) messenger RNA to lower production of AT in the liver. Fitusiran increases thrombin generation and has the potential for the research of the hemophilia[1].


Catalog Number I041222
Purity ≥95%
Reference

[1]. Pasi KJ, et al. Targeting of antithrombin in hemophilia A or B with investigational siRNA therapeutic fitusiran-Results of the phase 1 inhibitor cohort. J Thromb Haemost. 2021;19(6):1436-1446.
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