For research use only. Not for therapeutic Use.
Novel non-peptide galanin GAL<sub>1</sub> and GAL<sub>2</sub> receptor agonist (K<sub>i</sub> values are 11.7 and 34.1 <span class=/’symbol/’>μ</span>M respectively). Stimulates insulin release in isolated pancreatic islets from normal and diabetic rats. Systemically active <em>in vivo</em>; displays anticonvulsant activity following i.p. administration in mice. Central and peripheral administration also transiently inhibits food intake in rats and mice.
| Catalog Number | P000144 |
| CAS Number | 475115-35-6 |
| Synonyms | 3-Cyclohexyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-lysinamide |
| Molecular Formula | C40H46N4O6 |
| Purity | ≥95% |
| Target | Neuronal Signaling |
| Solubility | Soluble to 67.88 mg/ml in DMSO and to 16.97 mg/ml in ethanol with gentle warming |
| Storage | Desiccate at -20C |
| IUPAC Name | 9H-fluoren-9-ylmethyl N-[(2S)-1-[[(2S)-6-amino-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxohexan-2-yl]amino]-3-cyclohexyl-1-oxopropan-2-yl]carbamate |
| InChI | InChI=1S/C40H46N4O6/c1-25-21-37(45)50-36-23-27(18-19-28(25)36)42-38(46)34(17-9-10-20-41)43-39(47)35(22-26-11-3-2-4-12-26)44-40(48)49-24-33-31-15-7-5-13-29(31)30-14-6-8-16-32(30)33/h5-8,13-16,18-19,21,23,26,33-35H,2-4,9-12,17,20,22,24,41H2,1H3,(H,42,46)(H,43,47)(H,44,48)/t34-,35-/m0/s1 |
| InChIKey | IKNOZZKXIDSTRN-PXLJZGITSA-N |
| SMILES | CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C(CCCCN)NC(=O)C(CC3CCCCC3)NC(=O)OCC4C5=CC=CC=C5C6=CC=CC=C46 |
