Ganciclovir-d5

• CAT Number: R005442
• CAS Number: 1189966-73-1
• Molecular Formula: C9H13N5O4
• Molecular Weight: 260.265
• Purity: ≥95%
• Synonyms: 2-Amino-1,9-dihydro-9-[[2-hydroxy-1-(hydroxymethyl)ethoxy-d5]methyl]-6H-purin-6-one; 2’-NDG-d5; 2’-Nor-2’-deoxyguanosine-d5; 9-(1,3-Dihydroxy-2-propoxymethyl)?guanine-d5; BW 759-d5; BW 759U-d5; BW-B 759U-d5; Biolf 62-d5; DHPG-d5; Denosine-d5; Gancycl
• Storage: 2°C to 8°C
• Related CAS: 82410-32-0 (unlabeled)
• IUPAC Name: 2-amino-9-[(1,1,2,3,3-pentadeuterio-1,3-dihydroxypropan-2-yl)oxymethyl]-3H-purin-6-one
• InChI: InChI=1S/C9H13N5O4/c10-9-12-7-6(8(17)13-9)11-3-14(7)4-18-5(1-15)2-16/h3,5,15-16H,1-2,4H2,(H3,10,12,13,17)/i1D2,2D2,5D
• InChIKey: IRSCQMHQWWYFCW-QJWYSIDNSA-N
• SMILES: C1=NC2=C(N1COC(CO)CO)NC(=NC2=O)N

Ganciclovir-d5 is a deuterated form of Ganciclovir, featuring five deuterium atoms. This isotopically labeled compound is crucial for antiviral research, particularly in studies focused on the treatment of cytomegalovirus (CMV) infections. The incorporation of deuterium enhances the stability of the molecule and allows for precise tracking in mass spectrometry, making Ganciclovir-d5 an invaluable tool for pharmacokinetic and metabolic studies. It is ideal for researchers developing and optimizing antiviral therapies, providing reliable data for understanding the drug’s efficacy, metabolism, and resistance mechanisms in the context of CMV and other viral infections.