Ganglioside GM3 (sodium salt)

• CAT Number: R065080
• CAS Number: 54827-14-4
• Molecular Formula: C59H107N2O21 • Na
• Molecular Weight: 1203.5
• Purity: ≥95%
• Synonyms: Hematoside;Sialosyllactosylceramide
• Storage: -20°C
• InChI: InChI=1S/C59H108N2O21.Na/c1-4-6-8-10-12-14-16-18-19-21-23-25-27-29-31-33-46(69)61-40(41(66)32-30-28-26-24-22-20-17-15-13-11-9-7-5-2)38-77-56-51(73)50(72)53(45(37-64)79-56)80-57-52(74)55(49(71)44(36-63)78-57)82-59(58(75)76)34-42(67)47(60-39(3)65)54(81
• InChIKey: GGQRTSSCXQEZNW-BLVJLEROSA-M
• SMILES: O[C@@H]1[C@@H]([C@H]([C@@H](O[C@@H]1CO)O[C@H]2[C@@H]([C@H]([C@@H](O[C@@H]2CO)OC[C@@]([H])([C@](O)(/C=C/CCCCCCCCCCCCC)[H])NC(CCCCCCCCCCCCCCCCC)=O)O)O)O)O[C@]3(O[C@H]([C@@H]([C@H](C3)O)NC(C)=O)[C@@]([H])([C@]([H])(O)CO)O)C([O-])=O.[Na+]

Ganglioside GM3 (sodium salt) (Cat.No:R065080) is a complex lipid molecule found in cell membranes, particularly in nerve cells. It plays a role in cell signaling, cell adhesion, and cellular recognition processes. Ganglioside GM3 has implications in neurobiology and is of interest in research related to neural development and cell-membrane interactions.

Reference

1.Mukherjee, P.,Faber, A.C.,Shelton, L.M., et al. Thematic review series: Sphingolipids. Ganglioside GM3 suppresses the proangiogenic effects of vascular endothelial growth factor and ganglioside GD1a. Journal of Lipid Research 49(5), 929-938 (2008).