GAPDH inhibitor compound F8

• CAT Number: I047683
• CAS Number: 252212-58-1
• Molecular Formula: C20H18N2O5
• Molecular Weight: 366.37
• Purity: ≥95%
• IUPAC Name: 2,5-bis[3-(oxiran-2-ylmethoxy)phenyl]-1,3,4-oxadiazole
• InChI: InChI=1S/C20H18N2O5/c1-3-13(7-15(5-1)23-9-17-11-25-17)19-21-22-20(27-19)14-4-2-6-16(8-14)24-10-18-12-26-18/h1-8,17-18H,9-12H2
• SMILES: C1C(O1)COC2=CC=CC(=C2)C3=NN=C(O3)C4=CC(=CC=C4)OCC5CO5

GAPDH inhibitor compound F8 is a non-cysteine-targeting covalent GAPDH inhibitor.
Keywords: GAPDH inhibitor compound F8 | Supplier | GAPDH inhibitor | CAS [252212-58-1] | Glyceraldehyde 3-phosphate | GAPDH | Inhibitor | Enzymes | Glycolysis | Glyceraldehyde-3-phosphate dehydrogenase

Reference

Y Jung et al. Discovery of Non-Cysteine-Targeting Covalent Inhibitors by Activity-Based Proteomic Screening with a Cysteine-Reactive Probe. ACS Chem Biol. 2022 Feb 18;17(2):340-347.