GB111-NH2 hydrochloride

• CAT Number: I040225
• Molecular Formula: C33H40ClN3O6
• Molecular Weight: 610.14
• Purity: ≥95%
• Synonyms: [(3S)-7-amino-2-oxo-3-[[(2S)-3-phenyl-2-(phenylmethoxycarbonylamino)propanoyl]amino]heptyl] 2,6-dimethylbenzoate;hydrochloride
• InChI: InChI=1S/C33H39N3O6.ClH/c1-23-12-11-13-24(2)30(23)32(39)41-22-29(37)27(18-9-10-19-34)35-31(38)28(20-25-14-5-3-6-15-25)36-33(40)42-21-26-16-7-4-8-17-26;/h3-8,11-17,27-28H,9-10,18-22,34H2,1-2H3,(H,35,38)(H,36,40);1H/t27-,28-;/m0./s1
• InChIKey: LEQYHRMMCXGQOI-DHBRAOIWSA-N
• SMILES: CC1=C(C(=CC=C1)C)C(=O)OCC(=O)C(CCCCN)NC(=O)C(CC2=CC=CC=C2)NC(=O)OCC3=CC=CC=C3.Cl

GB111-NH2 hydrochloride is a cysteine cathepsin inhibitor, and can be used for cancer study[1].

Reference

[1]. Salpeter SJ, et al. A novel cysteine cathepsin inhibitor yields macrophage cell death and mammary tumor regression. Oncogene. 2015;34(50):6066-6078.
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