For research use only. Not for therapeutic Use.
GDC-6036-NH is from patent WO2020097537A2, and a precursor of compound 17 a/b. Compound 17 a/b is a RAS inhibitor and can be used in cancer research[1].
| Catalog Number | I043427 |
| CAS Number | 2417918-80-8 |
| Synonyms | 6-[6-chloro-8-fluoro-4-[(2S)-2-methylpiperazin-1-yl]-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]quinazolin-7-yl]-4-methyl-5-(trifluoromethyl)pyridin-2-amine |
| Molecular Formula | C26H30ClF4N7O |
| Purity | ≥95% |
| InChI | InChI=1S/C26H30ClF4N7O/c1-13-9-18(32)34-23(20(13)26(29,30)31)19-17(27)10-16-22(21(19)28)35-25(39-12-15-5-4-7-37(15)3)36-24(16)38-8-6-33-11-14(38)2/h9-10,14-15,33H,4-8,11-12H2,1-3H3,(H2,32,34)/t14-,15-/m0/s1 |
| InChIKey | XPOSONRWHCKUDU-GJZGRUSLSA-N |
| SMILES | CC1CNCCN1C2=NC(=NC3=C(C(=C(C=C32)Cl)C4=C(C(=CC(=N4)N)C)C(F)(F)F)F)OCC5CCCN5C |
| Reference | [1]. Malhotra Sushant, et al. FUSED RING COMPOUNDS. WO2020097537A2. |
