GEA-5024

• CAT Number: I027995
• CAS Number: 144575-52-0
• Molecular Formula: C8H10ClN4O
• Molecular Weight: 213.64
• Purity: 98%
• Synonyms: GEA-5024; GEA 5024; GEA5024
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 1,2,3,4-Oxatriazolium, 5-amino-3-(3-chloro-2-methylphenyl)-, inner salt
• InChI: InChI=1S/C8H10ClN4O/c1-5-6(9)3-2-4-7(5)13-11-8(10)14-12-13/h2-4H,12H2,1H3,(H2,10,11)
• InChIKey: BBEKNSDKHJONTM-UHFFFAOYSA-N
• SMILES: Cc1c(Cl)cccc1[N-]2[NH2+]OC(=N2)N

GEA-5024(CAT: I027995) is a selective 5-hydroxytryptamine 4 (5-HT₄) receptor agonist. By activating 5-HT₄ receptors, GEA-5024 enhances acetylcholine release in the gastrointestinal tract, promoting gastric motility and improving gut transit. This mechanism makes it a promising candidate for treating gastrointestinal motility disorders, such as gastroparesis and chronic constipation. Additionally, 5-HT₄ receptor agonists have shown potential in neurological research for cognitive enhancement and memory improvement due to their influence on central cholinergic pathways. GEA-5024 is a valuable compound in gastroenterology and neuroscience research for developing targeted therapies to regulate digestive and cognitive functions.