GEA-5024

• CAT Number: I027995
• CAS Number: 144575-52-0
• Molecular Formula: C8H10ClN4O
• Molecular Weight: 213.64
• Purity: 98%
• Synonyms: GEA-5024; GEA 5024; GEA5024
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 1,2,3,4-Oxatriazolium, 5-amino-3-(3-chloro-2-methylphenyl)-, inner salt
• InChI: InChI=1S/C8H10ClN4O/c1-5-6(9)3-2-4-7(5)13-11-8(10)14-12-13/h2-4H,12H2,1H3,(H2,10,11)
• InChIKey: BBEKNSDKHJONTM-UHFFFAOYSA-N
• SMILES: Cc1c(Cl)cccc1[N-]2[NH2+]OC(=N2)N

GEA-5024 is a nitric oxide-releasing compound.

Reference

1. Kapur S, Bédard S, Marcotte B, Côté CH, Marette A. Expression of nitric oxide synthase in skeletal muscle: a novel role for nitric oxide as a modulator of insulin action. Diabetes. 1997 Nov;46(11):1691-700. doi: 10.2337/diab.46.11.1691. PMID: 9356014.
2. Wanikiat P, Woodward DF, Armstrong RA. Investigation of the role of nitric oxide and cyclic GMP in both the activation and inhibition of human neutrophils. Br J Pharmacol. 1997 Nov;122(6):1135-45. doi: 10.1038/sj.bjp.0701477. PMID: 9401778; PMCID: PMC1565036.