Gemcitabine Monophosphate

• CAT Number: R030832
• CAS Number: 116371-67-6
• Molecular Formula: C₉H₁₂F₂N₃O₇P
• Molecular Weight: 343.18
• Purity: ≥95%
• Synonyms: 2’,2’-difluorodeoxycytidine Monophosphate; Gemcitabine 5’-phosphate
• Target: Apoptosis
• Storage: -20°C

Gemcitabine Monophosphate (CAT: R030832)  is a phosphorylated derivative of gemcitabine, a nucleoside analog chemotherapy drug used in the treatment of various cancers. Its mode of action involves being a prodrug that is converted to gemcitabine diphosphate and gemcitabine triphosphate intracellularly. These active forms inhibit DNA synthesis and replication, leading to cell death. Gemcitabine is commonly used in pancreatic, breast, lung, and bladder cancers. By interfering with DNA replication, Gemcitabine Monophosphate halts tumor growth, making it a valuable chemotherapeutic agent in clinical oncology