For research use only. Not for therapeutic Use.
Gemfibrozil-d6 (CAS: 1184986-45-5), a premium pharmaceutical research compound designed for advanced lipid metabolism studies. As a deuterated analog of Gemfibrozil, it offers enhanced stability and improved pharmacokinetic properties. Gemfibrozil-d6 is ideal for use in pharmacological and biochemical research, providing precise and reliable data for your studies. This high-purity compound ensures consistent results, aiding in the development of novel lipid-regulating therapies. Trusted by leading laboratories, Gemfibrozil-d6 is your go-to solution for cutting-edge metabolic research. Unlock new possibilities in lipid metabolism with Gemfibrozil-d6, where innovation meets reliability.
| Catalog Number | S000260 |
| CAS Number | 1184986-45-5 |
| Molecular Formula | C15H16D6O3 |
| Purity | ≥95% |
| Target | Vitamin D Related/Nuclear Receptor |
| IUPAC Name | 5-(2,5-dimethylphenoxy)-2,2-bis(trideuteriomethyl)pentanoic acid |
| InChI | InChI=1S/C15H22O3/c1-11-6-7-12(2)13(10-11)18-9-5-8-15(3,4)14(16)17/h6-7,10H,5,8-9H2,1-4H3,(H,16,17)/i3D3,4D3 |
| InChIKey | HEMJJKBWTPKOJG-LIJFRPJRSA-N |
| SMILES | [2H]C([2H])([2H])C(CCCOC1=C(C=CC(=C1)C)C)(C(=O)O)C([2H])([2H])[2H] |
| Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Pahan K, et al. Gemfibrozil, a lipid-lowering drug, inhibits the induction of nitric-oxide synthase in human astrocytes. J Biol Chem. 2002 Nov 29;277(48):45984-91. Epub 2002 Sep 18. [3]. Almad A, et al. The PPAR alpha agonist gemfibrozil is an ineffective treatment for spinal cord injured mice. Exp Neurol. 2011 Dec;232(2):309-17. [4]. Wang JS, et al. Gemfibrozil inhibits CYP2C8-mediated cerivastatin metabolism in human liver microsomes. Drug Metab Dispos. 2002 Dec;30(12):1352-6. |
