Gemifioxacin

• CAT Number: M044458
• CAS Number: 175463-14-6
• Molecular Formula: C18H20FN5O4
• Molecular Weight: 389.39
• Purity: ≥95%
• Target: Antibiotic
• Storage: -20°C
• IUPAC Name: 7-[(4Z)-3-(aminomethyl)-4-methoxyiminopyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid
• InChI: InChI=1S/C18H20FN5O4/c1-28-22-14-8-23(6-9(14)5-20)17-13(19)4-11-15(25)12(18(26)27)7-24(10-2-3-10)16(11)21-17/h4,7,9-10H,2-3,5-6,8,20H2,1H3,(H,26,27)/b22-14+
• InChIKey: ZRCVYEYHRGVLOC-HYARGMPZSA-N
• SMILES: CO/N=C/1\CN(CC1CN)C2=C(C=C3C(=O)C(=CN(C3=N2)C4CC4)C(=O)O)F

Gemifloxacin（Cat No.:M044458）is a broad-spectrum fluoroquinolone antibiotic used to treat respiratory tract infections, including acute bacterial exacerbations of chronic bronchitis and community-acquired pneumonia. It inhibits bacterial DNA gyrase and topoisomerase IV, essential enzymes for DNA replication and repair, leading to bacterial cell death. Gemifloxacin is effective against both Gram-positive and Gram-negative bacteria, with enhanced activity against Streptococcus pneumoniae and Haemophilus influenzae. Its favorable pharmacokinetic profile and once-daily dosing make it a convenient option. Gemifloxacin is also studied for its role in addressing fluoroquinolone resistance and optimizing antibacterial therapy.