For research use only, not for therapeutic use.
Gemigliptin (Zemiglo, LC15-0444) is a potent, selective and long-acting dipeptidyl peptidase 4 (DPP 4) inhibitor with a Ki of 7.25 nM. Gemigliptin shows at least >23,000-fold selectivity for DPP-4 over various proteases and peptidases, including DPP-8, DPP-9, and fibroblast activation protein (FAP)-α.
| Catalog Number | R027295 |
| CAS Number | 911637-19-9 |
| Molecular Formula | C18H19F8N5O2 |
| Purity | ≥95% |
| Storage | 3 years -20°C powder |
| SMILES | NC(CN1CC(F)(F)CCC1=O)CC(=O)N2CCC3=C(C2)N=C(N=C3C(F)(F)F)C(F)(F)F |
| Reference | [1] Sung-Ho Kim, et al. Eur J Pharmacol. 2016 Oct 5;788:54-64. |
