Gemigliptin

For research use only, not for therapeutic use.

  • CAT Number: R027295
  • CAS Number: 911637-19-9
  • Molecular Formula: C18H19F8N5O2
  • Molecular Weight: 489.36
  • Purity: ≥95%
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Gemigliptin (Zemiglo, LC15-0444) is a potent, selective and long-acting dipeptidyl peptidase 4 (DPP 4) inhibitor with a Ki of 7.25 nM. Gemigliptin shows at least >23,000-fold selectivity for DPP-4 over various proteases and peptidases, including DPP-8, DPP-9, and fibroblast activation protein (FAP)-α.


Catalog Number R027295
CAS Number 911637-19-9
Molecular Formula C18H19F8N5O2
Purity ≥95%
Storage 3 years -20°C powder
SMILES NC(CN1CC(F)(F)CCC1=O)CC(=O)N2CCC3=C(C2)N=C(N=C3C(F)(F)F)C(F)(F)F
Reference

[1] Sung-Ho Kim, et al. Eur J Pharmacol. 2016 Oct 5;788:54-64.
[2] Sung-Ho Kim, et al. Arch Pharm Res. 2013 Oct;36(10):1185-8.

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