Genistin

• CAT Number: I003937
• CAS Number: 529-59-9
• Molecular Formula: C₂₁H₂₀O₁₀
• Molecular Weight: 432.4
• Purity: ≥95%
• Synonyms: NSC 5112
• Solubility: DMSO: ≥ 43 mg/mL
• Storage: Store at -20°C
• IUPAC Name: 5-hydroxy-3-(4-hydroxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one
• InChI: InChI=1S/C21H20O10/c22-7-15-18(26)19(27)20(28)21(31-15)30-11-5-13(24)16-14(6-11)29-8-12(17(16)25)9-1-3-10(23)4-2-9/h1-6,8,15,18-24,26-28H,7H2/t15-,18-,19+,20-,21-/m1/s1
• InChIKey: ZCOLJUOHXJRHDI-CMWLGVBASA-N
• SMILES: C1=CC(=CC=C1C2=COC3=CC(=CC(=C3C2=O)O)OC4C(C(C(C(O4)CO)O)O)O)O

Genistin (Cat.No:I003937) is a phytoestrogen found in various plants, particularly in soybeans. It belongs to the class of isoflavones and has been studied for its potential health benefits. Genistin exhibits antioxidant and estrogenic properties, which may contribute to its role in promoting cardiovascular health and reducing the risk of certain diseases.

Reference

[1]. Russo A, et al. Genistin inhibits UV light-induced plasmid DNA damage and cell growth in human melanoma cells. The Journal of nutritional biochemistry, 2006, 17 (2): 103-108
[2]. Masayoshi Yamaguchi, et al. Anabolic effect of genistein and genistin on bone metabolism in the femoral-metaphyseal tissues of elderly rats: The genistein effect is enhanced by zinc. Molecular and Cellular Biochemistry January, 1998, Volume 178, Issue 1-2, pp 377-382
[3]. Jefferson WN, et al. Oral exposure to genistin, the glycosylated form of genistein, during neonatal life adversely affects the female reproductive system. Environ Health Perspect. 2009 Dec;117(12):1883-9.
[4]. E. Farmakalidis, et al. Oestrogenic potency of genistin and daidzin in mice. Food and Chemical Toxicology Volume 23, Issue 8, August 1985, Pages 741–745