Gentamicin C2 sulfate

• CAT Number: R000703
• CAS Number: 25876-11-3
• Molecular Formula: C20H41N5O7 xH2SO4 (lot specific)
• Molecular Weight: 463.57
• Purity: ≥95%
• Storage: -20°C
• IUPAC Name: (2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,6S)-3-amino-6-[(1R)-1-aminoethyl]oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol
• InChI: InChI=1S/C20H41N5O7/c1-8(21)12-5-4-9(22)18(30-12)31-15-10(23)6-11(24)16(13(15)26)32-19-14(27)17(25-3)20(2,28)7-29-19/h8-19,25-28H,4-7,21-24H2,1-3H3/t8-,9-,10+,11-,12+,13+,14-,15-,16+,17-,18-,19-,20+/m1/s1
• InChIKey: XUFIWSHGXVLULG-IDLVJFIQSA-N
• SMILES: C[C@H]([C@@H]1CC[C@H]([C@H](O1)O[C@@H]2[C@H](C[C@H]([C@@H]([C@H]2O)O[C@@H]3[C@@H]([C@H]([C@@](CO3)(C)O)NC)O)N)N)N)N

Gentamicin C2 sulfate（Cat No.:R000703）is one of the major components of the gentamicin complex, an aminoglycoside antibiotic produced by Micromonospora purpurea. It is commonly formulated as a sulfate salt to enhance solubility and stability. Gentamicin C2 consists of a central 2-deoxystreptamine ring linked to amino sugars, exhibiting potent bactericidal activity by binding to the 30S ribosomal subunit, thereby inhibiting protein synthesis in susceptible Gram-negative and some Gram-positive bacteria. It is widely used to treat serious infections, including those resistant to other antibiotics, and is administered with care due to potential nephrotoxicity and ototoxicity.