For research use only. Not for therapeutic Use.
Gentamicin Sulfate(Cat No.:A000448)is a broad-spectrum aminoglycoside antibiotic effective against a wide range of gram-negative and some gram-positive bacteria. It binds to the bacterial 30S ribosomal subunit, inhibiting protein synthesis, which results in bacterial cell death. Often used in severe infections, including sepsis and respiratory, urinary, and bone infections, Gentamicin Sulfate is essential in treating multidrug-resistant strains. It is also valuable in research on antimicrobial resistance, synergistic antibiotic therapies, and bacterial protein synthesis inhibition. Its potency and reliability make it a cornerstone in combating serious bacterial infections.
Catalog Number | A000448 |
CAS Number | 1405-41-0 |
Synonyms | NSC-82261, SCH9724 |
Molecular Formula | C21H45N5O11S |
Purity | ≥95% |
Target | Antibiotic |
Solubility | Limited solubility |
Storage | Store at -20°C |
Reference | <p>Davis, Bernard D. /Mechanism of Bactericidal Action of Aminoglycosides./References<em>Microbiological Reviews</em> 51.3 (1987): 341-50.</p><p>Sarna, Katarzyna, and Agata Blazewicz. /Determination of Gentamicin Sulphate Composition and Related Substances in Pharmaceutical Preparations by LC with Charged Aerosol Detection./ <em>PubMed</em> (2010)</p><p>Vydrin, A. F. /Component Composition of Gentamicin Sulfate Preparations./ Pharmaceutical Chemistry Journal 37.8 (2003): 448-49. Web. 15 Oct. 2013.</p></span></p> |