For research use only. Not for therapeutic Use.
Gentisein (NSC 329491), the major metabolite of Mangiferin, shows the most potent serotonin uptake inhibition with an IC50 value of 4.7 µM[1][2].
| Catalog Number | I028003 |
| CAS Number | 529-49-7 |
| Synonyms | 1,3,7-trihydroxyxanthen-9-one |
| Molecular Formula | C13H8O5 |
| Purity | ≥95% |
| InChI | InChI=1S/C13H8O5/c14-6-1-2-10-8(3-6)13(17)12-9(16)4-7(15)5-11(12)18-10/h1-5,14-16H |
| InChIKey | JJUNZBRHHGLJQW-UHFFFAOYSA-N |
| SMILES | C1=CC2=C(C=C1O)C(=O)C3=C(C=C(C=C3O2)O)O |
| Reference | [1]. Wang H, et al. Identification and determination of four metabolites of mangiferin in rat urine. J Pharm Biomed Anal. 2007;45(5):793-798. [2]. Tzankova, Virginia et al. (2010). Inhibition of 5-HT uptake by some constituents of Hypericum annulatum in rat brain in vitro. Pharmacologyonline. 2. |
