Ginkgolic Acid

• CAT Number: I002561
• CAS Number: 20261-38-5
• Molecular Formula: C20H32O3
• Molecular Weight: 320.47
• Purity: ≥95%
• Target: Bacterial
• Solubility: 10 mM in DMSO
• Storage: Store at -20°C
• IC50: Inhibiting the biofilm formation of S. mutans (MBIC (50) = 4 μg/mL); reduced 1-day-developed biofilm of S. mutans by 50 % or more at low concentration (MBRC (50) = 32 μg/mL).
• IUPAC Name: 2-hydroxy-6-tridecylbenzoic acid
• InChI: InChI=1S/C20H32O3/c1-2-3-4-5-6-7-8-9-10-11-12-14-17-15-13-16-18(21)19(17)20(22)23/h13,15-16,21H,2-12,14H2,1H3,(H,22,23)
• InChIKey: VEPUCZUJLKAVNM-UHFFFAOYSA-N
• SMILES: CCCCCCCCCCCCCC1=C(C(=CC=C1)O)C(=O)O

Ginkgolic Acid（Cat No.:I002561）is a bioactive compound derived from the leaves and seeds of the Ginkgo biloba tree, known for its antimicrobial, anticancer, and anti-inflammatory properties. Structurally similar to anacardic acid, it has been studied for its potential to inhibit growth in bacteria, fungi, and cancer cells by targeting key cellular pathways. However, ginkgolic acid is also associated with allergenic and toxic effects, which limits its use. Despite these concerns, it remains a focus in natural product research for its unique bioactivity and potential applications in pharmacology and alternative medicine.

Reference

[1]. He J, et al. Effects of ginkgoneolic acid on the growth, acidogenicity, adherence, and biofilm of Streptococcus mutans in vitro. Folia Microbiol (Praha). 2013 Mar;58(2):147-53.