Ginkgolide B

• CAT Number: I001907
• CAS Number: 15291-77-7
• Molecular Formula: C20H24O10
• Molecular Weight: 424.4
• Purity: ≥95%
• Synonyms: BN 52021;BN 52051
• Target: PAFR
• Solubility: DMSO: ≥ 30 mg/mL
• Storage: 3 years -20℃ powder
• IUPAC Name: 8-tert-butyl-6,12,17-trihydroxy-16-methyl-2,4,14,19-tetraoxahexacyclo[8.7.2.01,11.03,7.07,11.013,17]nonadecane-5,15,18-trione
• InChI: InChI=1S/C20H24O10/c1-6-12(23)28-11-9(21)18-8-5-7(16(2,3)4)17(18)10(22)13(24)29-15(17)30-20(18,14(25)27-8)19(6,11)26/h6-11,15,21-22,26H,5H2,1-4H3
• InChIKey: SQOJOAFXDQDRGF-RZXAINQJSA-N
• SMILES: CC1C(=O)OC2C1(C34C(=O)OC5C3(C2O)C6(C(C5)C(C)(C)C)C(C(=O)OC6O4)O)O

Ginkgolide B (Cat.No:I001907) is a bioactive compound extracted from Ginkgo biloba leaves. It belongs to the family of terpenes and has been extensively researched for its pharmacological properties. Ginkgolide B exhibits potent antiplatelet and neuroprotective effects, making it a potential candidate for the treatment of cardiovascular diseases and neurological disorders.

Reference

[1]. Jean R. Rapin, et al. In vitro and in vivo effects of an extract of Ginkgo biloba (EGb 761), ginkgolide B, and bilobalide on apoptosis in primary cultures of rat hippocampal neurons. Drug Development Research, 1998, 45 (1):1-43
[2]. Matyas Koltai, et al. Ginkgolide B protects isolated hearts against arrhythmias induced by ischemia but not reperfusion. European Journal of Pharmacology, 1989, 164 (2): 293-302