Ginsenoside Re

• CAT Number: I003911
• CAS Number: 52286-59-6
• Molecular Formula: C48H82O18
• Molecular Weight: 947.2
• Purity: ≥95%
• Synonyms: Chikusetsusaponin IVc;NSC 308877;Panaxoside Re;Sanchinoside Re
• Target: NF-κB
• Solubility: 10 mM in DMSO
• Storage: Store at -20°C
• IUPAC Name: (2S,3R,4R,5R,6S)-2-[(2R,3R,4S,5S,6R)-2-[[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-6-methyloxane-3,4,5-triol
• InChI: InChI=1S/C48H82O18/c1-21(2)11-10-14-48(9,66-42-38(60)35(57)32(54)26(19-49)63-42)23-12-16-46(7)30(23)24(51)17-28-45(6)15-13-29(52)44(4,5)40(45)25(18-47(28,46)8)62-43-39(36(58)33(55)27(20-50)64-43)65-41-37(59)34(56)31(53)22(3)61-41/h11,22-43,49-60H,10,12-20H2,1-9H3/t22-,23-,24+,25-,26+,27+,28+,29-,30-,31-,32+,33+,34+,35-,36-,37+,38+,39+,40-,41-,42-,43+,45+,46+,47+,48-/m0/s1
• InChIKey: PWAOOJDMFUQOKB-WCZZMFLVSA-N
• SMILES: CC1C(C(C(C(O1)OC2C(C(C(OC2OC3CC4(C(CC(C5C4(CCC5C(C)(CCC=C(C)C)OC6C(C(C(C(O6)CO)O)O)O)C)O)C7(C3C(C(CC7)O)(C)C)C)C)CO)O)O)O)O)O

Ginsenoside Re (Cat.No:I003911) is a natural compound derived from ginseng, a popular herb in traditional medicine. It falls under the category of triterpenoid saponins and has been extensively researched for its potential health benefits. Ginsenoside Re exhibits anti-inflammatory, antioxidant, and neuroprotective properties, highlighting its potential therapeutic applications in promoting overall wellness and cognitive function.

Reference

[1]. Wang L, et al. Ginsenoside Re Promotes Nerve Regeneration by Facilitating the Proliferation, Differentiation and Migration of Schwann Cells via the ERK- and JNK-Dependent Pathway in Rat Model of Sciatic Nerve Crush Injury. Cell Mol Neurobiol. 2015 Mar 17.

[2]. Sukrittanon S, et al. Ginsenoside Re enhances small-conductance Ca(2+)-activated K(+) current in human coronary artery endothelial cells. Life Sci. 2014 Oct 12;115(1-2):15-21.

[3]. Nam Y, et al. Ginsenoside Re protects methamphetamine-induced mitochondrial burdens and proapoptosis via genetic inhibition of protein kinase C δ in human neuroblastoma dopaminergic SH-SY5Y cell lines. J Appl Toxicol. 2014 Dec 18.

[4]. Su X, et al. Ginsenoside Re as an adjuvant to enhance the immune response to the inactivated rabies virus vaccine in mice. Int Immunopharmacol. 2014 Jun;20(2):283-9.