For research use only. Not for therapeutic Use.
Ginsenoside Rh2（Cat No.:I004875）is a bioactive compound found in ginseng, a traditional herbal medicine known for its health benefits. It is a protopanaxadiol-type saponin derived from ginsenoside Rb1 and is primarily recognized for its potential anticancer, anti-inflammatory, and neuroprotective effects. Studies suggest that Ginsenoside Rh2 may inhibit tumor cell growth, induce apoptosis in cancer cells, and enhance immune function. Additionally, it has shown potential in improving cognitive function and reducing stress. However, more clinical research is needed to fully understand its therapeutic efficacy and safety profile.
| Catalog Number | I004875 |
| CAS Number | 78214-33-2 |
| Molecular Formula | C36H62O8 |
| Purity | ≥95% |
| Target | Metabolic Enzyme/Protease |
| Solubility | 10 mM in DMSO |
| Storage | 2-8°C |
| IUPAC Name | (2R,3R,4S,5S,6R)-2-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-17-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol |
| InChI | InChI=1S/C36H62O8/c1-20(2)10-9-14-36(8,42)21-11-16-35(7)27(21)22(38)18-25-33(5)15-13-26(32(3,4)24(33)12-17-34(25,35)6)44-31-30(41)29(40)28(39)23(19-37)43-31/h10,21-31,37-42H,9,11-19H2,1-8H3/t21-,22+,23+,24-,25+,26-,27-,28+,29-,30+,31-,33-,34+,35+,36-/m0/s1 |
| InChIKey | CKUVNOCSBYYHIS-IRFFNABBSA-N |
| SMILES | CC(=CCC[C@@](C)([C@H]1CC[C@@]2([C@@H]1[C@@H](C[C@H]3[C@]2(CC[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O)C)C)O)C)O)C |
| Reference | <p style=/line-height:25px/> <br>[2]. Shaoyi Li, et al. Ginsenoside Rh2 inhibits invasiveness of glioblastoma through modulation of VEGF-A. Tumor Biology <br>[3]. Ning Guan, et al. Ginsenoside Rh2 inhibits metastasis of glioblastoma multiforme through Akt-regulated MMP13. Tumor Biology, <br>[4]. Zhou J, et al. Ginsenoside Rh2 Suppresses Neovascularization in Xenograft Psoriasis Model. Cell Physiol Biochem 2015;36:980-987 </p> |
