Ginsenoside Rh2

• CAT Number: I004875
• CAS Number: 78214-33-2
• Molecular Formula: C36H62O8
• Molecular Weight: 622.87
• Purity: ≥95%
• Solubility: 10 mM in DMSO
• Storage: 2-8°C
• IUPAC Name: (2R,3R,4S,5S,6R)-2-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-17-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol
• InChI: InChI=1S/C36H62O8/c1-20(2)10-9-14-36(8,42)21-11-16-35(7)27(21)22(38)18-25-33(5)15-13-26(32(3,4)24(33)12-17-34(25,35)6)44-31-30(41)29(40)28(39)23(19-37)43-31/h10,21-31,37-42H,9,11-19H2,1-8H3/t21-,22+,23+,24-,25+,26-,27-,28+,29-,30+,31-,33-,34+,35+,36-/m0/s1
• InChIKey: CKUVNOCSBYYHIS-IRFFNABBSA-N
• SMILES: CC(=CCCC(C)(C1CCC2(C1C(CC3C2(CCC4C3(CCC(C4(C)C)OC5C(C(C(C(O5)CO)O)O)O)C)C)O)C)O)C

Ginsenoside Rh2 (Cat No.: I004875) is a triterpene saponin isolated from ginseng, which has high anti-inflammatory and anti-cancer activities. Ginsenoside Rh2 induces caspase-8 and caspase-9 activation. Ginsenoside Rh2 induces cancer cell apoptosis in a multi-pathway manner. If you need, please contact us in time, and we will reply as soon as possible within 24 hours.

Reference

[1]. Yan Zhu, et al. Ginsenoside Rh2 suppresses growth of uterine leiomyoma in vitro and in vivo and may regulate ERα/c-Src/p38 MAPK activity. Journal of Functional Foods
Volume 18, Part A, October 2015, Pages 73–82

[2]. Shaoyi Li, et al. Ginsenoside Rh2 inhibits invasiveness of glioblastoma through modulation of VEGF-A. Tumor Biology
July 2015

[3]. Ning Guan, et al. Ginsenoside Rh2 inhibits metastasis of glioblastoma multiforme through Akt-regulated MMP13. Tumor Biology,
April 2015

[4]. Zhou J, et al. Ginsenoside Rh2 Suppresses Neovascularization in Xenograft Psoriasis Model. Cell Physiol Biochem 2015;36:980-987