Glipizide-d11

• CAT Number: R005227
• CAS Number: 1189426-07-0
• Molecular Formula: C21H27N5O4S
• Molecular Weight: 456.605
• Purity: ≥95%
• Synonyms: N-[2-[4[[[(Cyclohexylamino-d11)carbonyl]amino]sulfonyl]phenyl]ethyl]-5-methylpyrazinecarboxamide; 1-(Cyclohexyl-d11)-3-[[p-[2-(5-methylpyrazinecarboxamido)?ethyl]phenyl]sulfonyl]urea; Aldiab-d11; Digrin-d11; Dipazide-d11; Glibenese-d11; Glibetin-d11
• Target: Potassium Channel
• Storage: Store at -20°C
• IUPAC Name: 5-methyl-N-[2-[4-[(1,2,2,3,3,4,4,5,5,6,6-undecadeuteriocyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]pyrazine-2-carboxamide
• InChI: InChI=1S/C21H27N5O4S/c1-15-13-24-19(14-23-15)20(27)22-12-11-16-7-9-18(10-8-16)31(29,30)26-21(28)25-17-5-3-2-4-6-17/h7-10,13-14,17H,2-6,11-12H2,1H3,(H,22,27)(H2,25,26,28)/i2D2,3D2,4D2,5D2,6D2,17D
• InChIKey: ZJJXGWJIGJFDTL-KVEFGMAKSA-N
• SMILES: 2H]C1(C(C(C(C(C1([2H])[2H])([2H])[2H])([2H])NC(=O)NS(=O)(=O)C2=CC=C(C=C2)CCNC(=O)C3=NC=C(N=C3)C)([2H])[2H])([2H])[2H])[2H]

Glipizide-d11 is a deuterated version of glipizide, a widely used oral hypoglycemic agent for treating type 2 diabetes. In this compound, eleven hydrogen atoms are replaced by deuterium, enhancing its stability and making it a valuable tool in pharmacokinetic and metabolic research. The deuterium labeling allows for precise tracking in studies using NMR spectroscopy and mass spectrometry, enabling detailed analysis of glipizide’s absorption, distribution, metabolism, and excretion. Glipizide-d11 is crucial for researchers focused on developing improved diabetes treatments and understanding the drug’s interaction with biological systems, offering greater accuracy and reliability in experimental results.