For research use only. Not for therapeutic Use.
GLP-1R agonist 10（Cat No.:I043510）is a novel peptide-based compound designed to activate the glucagon-like peptide-1 receptor (GLP-1R), which plays a key role in regulating blood sugar levels and appetite. By mimicking the action of the natural GLP-1 hormone, GLP-1R agonist 10 promotes insulin secretion, inhibits glucagon release, and slows gastric emptying, all of which help lower blood glucose levels. It is being investigated as a potential treatment for type 2 diabetes and obesity, offering a therapeutic alternative to current GLP-1R agonists with enhanced efficacy or extended duration of action.
| CAS Number | 2762515-25-1 |
| Synonyms | 2-[[4-[6-[(4-chloro-2-fluorophenyl)methyl]pyridin-2-yl]oxypiperidin-1-yl]methyl]-3-[[(2S)-oxetan-2-yl]methyl]imidazo[4,5-b]pyridine-5-carboxylic acid |
| Molecular Formula | C29H29ClFN5O4 |
| Purity | ≥95% |
| IUPAC Name | 2-[[4-[6-[(4-chloro-2-fluorophenyl)methyl]pyridin-2-yl]oxypiperidin-1-yl]methyl]-3-[[(2S)-oxetan-2-yl]methyl]imidazo[4,5-b]pyridine-5-carboxylic acid |
| InChI | InChI=1S/C29H29ClFN5O4/c30-19-5-4-18(23(31)15-19)14-20-2-1-3-27(32-20)40-21-8-11-35(12-9-21)17-26-33-24-6-7-25(29(37)38)34-28(24)36(26)16-22-10-13-39-22/h1-7,15,21-22H,8-14,16-17H2,(H,37,38)/t22-/m0/s1 |
| InChIKey | SDHYTOOEXFYXIT-QFIPXVFZSA-N |
| SMILES | C1CO[C@@H]1CN2C(=NC3=C2N=C(C=C3)C(=O)O)CN4CCC(CC4)OC5=CC=CC(=N5)CC6=C(C=C(C=C6)Cl)F |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
