For research use only. Not for therapeutic Use.
GLP-1R agonist 10 (Compound 109a) is a GLP-1 agonist with an EC50 of 0.051 nM[1].
| Catalog Number | I043510 |
| CAS Number | 2762515-25-1 |
| Synonyms | 2-[[4-[6-[(4-chloro-2-fluorophenyl)methyl]pyridin-2-yl]oxypiperidin-1-yl]methyl]-3-[[(2S)-oxetan-2-yl]methyl]imidazo[4,5-b]pyridine-5-carboxylic acid |
| Molecular Formula | C29H29ClFN5O4 |
| Purity | ≥95% |
| InChI | InChI=1S/C29H29ClFN5O4/c30-19-5-4-18(23(31)15-19)14-20-2-1-3-27(32-20)40-21-8-11-35(12-9-21)17-26-33-24-6-7-25(29(37)38)34-28(24)36(26)16-22-10-13-39-22/h1-7,15,21-22H,8-14,16-17H2,(H,37,38)/t22-/m0/s1 |
| InChIKey | SDHYTOOEXFYXIT-QFIPXVFZSA-N |
| SMILES | C1CN(CCC1OC2=CC=CC(=N2)CC3=C(C=C(C=C3)Cl)F)CC4=NC5=C(N4CC6CCO6)N=C(C=C5)C(=O)O |
| Reference | [1]. Qinghua Meng, et al. Heterocyclic glp-1 agonists. WO2022042691A1. |
