For research use only. Not for therapeutic Use.
Glucagon receptor antagonists-1 is a highly potent glucagon receptor antagonist.
Catalog Number | I003784 |
CAS Number | 503559-84-0 |
Synonyms | 1-[4-(4-fluoro-2-phenylmethoxyphenyl)-2,6-di(propan-2-yl)-5-[(E)-prop-1-enyl]pyridin-3-yl]ethanol |
Molecular Formula | C29H34FNO2 |
Purity | ≥95% |
InChI | InChI=1S/C29H34FNO2/c1-7-11-24-27(26(20(6)32)29(19(4)5)31-28(24)18(2)3)23-15-14-22(30)16-25(23)33-17-21-12-9-8-10-13-21/h7-16,18-20,32H,17H2,1-6H3/b11-7+ |
InChIKey | HERVQUFQZXZOBU-YRNVUSSQSA-N |
SMILES | CC=CC1=C(C(=C(N=C1C(C)C)C(C)C)C(C)O)C2=C(C=C(C=C2)F)OCC3=CC=CC=C3 |
Reference | [1]. Ladouceur, Gaetan H. et al. Integration of optimized substituent patterns to produce highly potent 4-aryl-pyridine glucagon receptor antagonists. Bioorganic & Medicinal Chemistry Letters (2002), 12(23), 3421-3424. |