Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Mal

• CAT Number: I042284
• CAS Number: 2345732-89-8
• Molecular Formula: C47H53N4O14P
• Molecular Weight: 928.92
• Purity: ≥95%
• Synonyms: [2-[(1S,2S,4R,6R,8S,9S,11S,12S,13R)-6-[4-[[3-[[(2S)-2-[[(2S)-2-[[2-(2,5-dioxopyrrol-1-yl)acetyl]amino]propanoyl]amino]propanoyl]amino]phenyl]methyl]phenyl]-11-hydroxy-9,13-dimethyl-16-oxo-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-8-yl]-2-oxoethyl] dihydrogen phosphate
• InChI: InChI=1S/C47H53N4O14P/c1-25(48-38(55)23-51-39(56)14-15-40(51)57)42(58)49-26(2)43(59)50-31-7-5-6-28(19-31)18-27-8-10-29(11-9-27)44-64-37-21-34-33-13-12-30-20-32(52)16-17-45(30,3)41(33)35(53)22-46(34,4)47(37,65-44)36(54)24-63-66(60,61)62/h5-11,14-17,19-20,25-26,33-35,37,41,44,53H,12-13,18,21-24H2,1-4H3,(H,48,55)(H,49,58)(H,50,59)(H2,60,61,62)/t25-,26-,33-,34-,35-,37+,41+,44+,45-,46-,47+/m0/s1
• InChIKey: PCHXBKCIRQOZOP-OWXFDGHLSA-N
• SMILES: C[C@@H](C(=O)N[C@@H](C)C(=O)NC1=CC=CC(=C1)CC2=CC=C(C=C2)[C@@H]3O[C@@H]4C[C@H]5[C@@H]6CCC7=CC(=O)C=C[C@@]7([C@H]6[C@H](C[C@@]5([C@@]4(O3)C(=O)COP(=O)(O)O)C)O)C)NC(=O)CN8C(=O)C=CC8=O

Glucocorticoid Receptor Agonist-1 Phosphate Ala-Ala-Mal（Cat No.:I042284）is a synthetic compound designed to activate the glucocorticoid receptor (GR), a key receptor involved in regulating inflammation, immune responses, and metabolism. The compound consists of a glucocorticoid receptor agonist linked to a peptide, Ala-Ala-Mal, which enhances its bioactivity and selectivity. By binding to the GR, this agonist aims to modulate immune responses, reduce inflammation, and improve conditions such as autoimmune diseases and inflammatory disorders. Its phosphate group may influence solubility or pharmacokinetics, optimizing the compound for therapeutic use in targeted treatments.