Glucosamine 6-sulfate

• CAT Number: I041024
• CAS Number: 91674-26-9
• Molecular Formula: C6H13NO8S
• Molecular Weight: 259.23
• Purity: ≥95%
• Synonyms: [(2R,3S,4R,5R)-5-amino-2,3,4-trihydroxy-6-oxohexyl] hydrogen sulfate
• IUPAC Name: [(2R,3S,4R,5R,6R)-5-amino-3,4,6-trihydroxyoxan-2-yl]methyl hydrogen sulfate
• InChI: InChI=1S/C6H13NO8S/c7-3(1-8)5(10)6(11)4(9)2-15-16(12,13)14/h1,3-6,9-11H,2,7H2,(H,12,13,14)/t3-,4+,5+,6+/m0/s1
• InChIKey: KRCSEEITTBNSQS-SLPGGIOYSA-N
• SMILES: C([C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)O)N)O)O)OS(=O)(=O)O

Glucosamine 6-sulfate(CAT: I041024) is a naturally occurring amino sugar that plays a critical role in the biosynthesis of glycosaminoglycans, essential components of cartilage and connective tissues. It is commonly used in the treatment of osteoarthritis, as it promotes cartilage repair and reduces inflammation by stimulating the production of proteoglycans and hyaluronic acid. This compound is also investigated in metabolic disease research for its potential effects on joint health, insulin sensitivity, and glucose metabolism. Glucosamine 6-sulfate is explored as a therapeutic option in managing conditions such as osteoarthritis and metabolic syndrome, where joint degradation and inflammation are prevalent.

Reference

[1]. Khan MA, et al. Two Small RNAs Conserved in Enterobacteriaceae Provide Intrinsic Resistance to Antibiotics Targeting the Cell Wall Biosynthesis Enzyme Glucosamine-6-Phosphate Synthase. Front Microbiol. 2016 Jun 15;7:908.
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