For research use only. Not for therapeutic Use.
Glufosfamide is a novel alkylating agent in which the active metabolite of isophosphoramide mustard is glycosidically linked to β-D-glucose.
| Catalog Number | M108613 |
| CAS Number | 132682-98-5 |
| Synonyms | (2S,3R,4S,5S,6R)-2-bis(2-chloroethylamino)phosphoryloxy-6-(hydroxymethyl)oxane-3,4,5-triol |
| Molecular Formula | C10H21Cl2N2O7P |
| Purity | ≥95% |
| InChI | InChI=1S/C10H21Cl2N2O7P/c11-1-3-13-22(19,14-4-2-12)21-10-9(18)8(17)7(16)6(5-15)20-10/h6-10,15-18H,1-5H2,(H2,13,14,19)/t6-,7-,8+,9-,10+/m1/s1 |
| InChIKey | PSVUJBVBCOISSP-SPFKKGSWSA-N |
| SMILES | C(CCl)NP(=O)(NCCCl)OC1C(C(C(C(O1)CO)O)O)O |
| Reference | [1]. DollnerR, et al. Ex vivo responsiveness of head and neck squamous cell carcinoma to glufosfamide, a novelalkylating agent. Anticancer Res. 2004 Sep-Oct;24(5A):2947-51. |
