For research use only. Not for therapeutic Use.
GLUT1-IN-2 (compound 17) is a GLUT1 inhibitor with an IC50 value of 12 μM. GLUT1-IN-2 shows inhibitory effect to Plasmodium falciparum hexose transporter PfHT with an IC50 value of 13 μM. GLUT1-IN-2 can be used for the research of infection[1].
GLUT1-IN-2 (0-100 μM) inhibits activities of GLUT1 and PfHT with IC50 values of 12 and 13 μM, respectively[1].
| Catalog Number | I042630 |
| CAS Number | 305357-89-5 |
| Synonyms | N-[3-(1H-benzimidazol-2-yl)phenyl]-3-methylbenzamide |
| Molecular Formula | C21H17N3O |
| Purity | ≥95% |
| InChI | InChI=1S/C21H17N3O/c1-14-6-4-8-16(12-14)21(25)22-17-9-5-7-15(13-17)20-23-18-10-2-3-11-19(18)24-20/h2-13H,1H3,(H,22,25)(H,23,24) |
| InChIKey | BFAZKDZNMRHORZ-UHFFFAOYSA-N |
| SMILES | CC1=CC(=CC=C1)C(=O)NC2=CC=CC(=C2)C3=NC4=CC=CC=C4N3 |
| Reference | [1]. Ortiz D, et al. Identification of Selective Inhibitors of the Plasmodium falciparum Hexose Transporter PfHT by Screening Focused Libraries of Anti-Malarial Compounds. PLoS One. 2015 Apr 20;10(4):e0123598. |
