For research use only. Not for therapeutic Use.
Glutaminase C-IN-1(Cat No.:I013858)is a selective inhibitor of the enzyme glutaminase C (GAC), which plays a key role in converting glutamine to glutamate, an essential neurotransmitter. GAC is involved in various cellular processes, including metabolism and signaling, and its dysregulation is associated with cancer, particularly in tumors that rely on glutamine metabolism for growth. By inhibiting GAC, Glutaminase C-IN-1 has been studied for its potential therapeutic applications in targeting metabolic pathways in cancer cells. Further research is needed to explore its efficacy, safety, and potential as a treatment for cancers with altered glutamine metabolism.
Catalog Number | I013858 |
CAS Number | 311795-38-7 |
Molecular Formula | C₂₇H₂₇BrN₂O |
Purity | ≥95% |
Target | Others |
Solubility | 10 mM in DMSO |
IUPAC Name | 5-[3-bromo-4-(dimethylamino)phenyl]-2,2-dimethyl-1,3,5,6-tetrahydrobenzo[a]phenanthridin-4-one |
InChI | InChI=1S/C27H27BrN2O/c1-27(2)14-19-24-18-8-6-5-7-16(18)9-11-21(24)29-26(25(19)23(31)15-27)17-10-12-22(30(3)4)20(28)13-17/h5-13,26,29H,14-15H2,1-4H3 |
InChIKey | NVFRRJQWRZFDLM-UHFFFAOYSA-N |
SMILES | CC1(CC2=C(C(NC3=C2C4=CC=CC=C4C=C3)C5=CC(=C(C=C5)N(C)C)Br)C(=O)C1)C |