Glutaminyl Cyclase Inhibitor 4

• CAT Number: I018082
• CAS Number: 2376329-36-9
• Molecular Formula: C₂₂H₃₃N₅O₃
• Molecular Weight: 415.53
• Purity: ≥95%

Glutaminyl Cyclase Inhibitor 4 (compound 90) is a potent, selective glutaminyl cyclase (QC) inhibitor with an IC50 of 6.1 nM. Glutaminyl Cyclase Inhibitor 4 is a potent anti-Alzheimer’s agent[1].

Reference

[1]. Hoang VH, et al. Discovery of Conformationally Restricted Human Glutaminyl Cyclase Inhibitors as Potent Anti-Alzheimer’s Agents by Structure-Based Design. J Med Chem. 2019 Aug 27.