Glutathione diethyl ester TFA

• CAT Number: I040099
• Molecular Formula: C16H26F3N3O8S
• Molecular Weight: 477.45
• Purity: ≥95%
• Synonyms: ethyl (2S)-2-amino-5-[[(2R)-1-[(2-ethoxy-2-oxoethyl)amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-5-oxopentanoate;2,2,2-trifluoroacetic acid
• InChI: InChI=1S/C14H25N3O6S.C2HF3O2/c1-3-22-12(19)7-16-13(20)10(8-24)17-11(18)6-5-9(15)14(21)23-4-2;3-2(4,5)1(6)7/h9-10,24H,3-8,15H2,1-2H3,(H,16,20)(H,17,18);(H,6,7)/t9-,10-;/m0./s1
• InChIKey: USGFUNMVEYPOIY-IYPAPVHQSA-N
• SMILES: CCOC(=O)CNC(=O)C(CS)NC(=O)CCC(C(=O)OCC)N.C(=O)(C(F)(F)F)O

Glutathione diethyl ester TFA (Cat No.: I040099) is a derivative of glutathione, a tripeptide composed of glutamine, cysteine, and glycine, modified with diethyl ester groups to enhance its cell permeability. The TFA (trifluoroacetate) salt form improves its solubility and stability for research purposes. This compound is commonly used in biochemical studies to explore glutathione’s role in cellular antioxidant defense, redox regulation, and detoxification processes. Glutathione diethyl ester TFA can be utilized in experiments investigating oxidative stress, enzyme activity, and cell signaling pathways.

Reference

[1]. E J Levy, et al. Transport of glutathione diethyl ester into human cells. Proc Natl Acad Sci U S A. 1993 Oct 1;90(19):9171-5.
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