Glutathione ethyl ester

• CAT Number: R064938
• CAS Number: 92614-59-0
• Molecular Formula: C12H21N3O6S
• Molecular Weight: 335.38
• Purity: ≥95%
• Synonyms: (2S)-2-amino-5-[[(2R)-1-[(2-ethoxy-2-oxoethyl)amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-5-oxopentanoic acid
• InChI: InChI=1S/C12H21N3O6S/c1-2-21-10(17)5-14-11(18)8(6-22)15-9(16)4-3-7(13)12(19)20/h7-8,22H,2-6,13H2,1H3,(H,14,18)(H,15,16)(H,19,20)/t7-,8-/m0/s1
• InChIKey: JKRODHBGNBKZLE-YUMQZZPRSA-N
• SMILES: CCOC(=O)CNC(=O)C(CS)NC(=O)CCC(C(=O)O)N

Glutathione ethyl ester(CAT: R064938) is a lipophilic, cell-permeable derivative of glutathione (GSH), a vital intracellular antioxidant involved in detoxification, redox balance, and immune function. The ethyl ester modification enhances membrane permeability, allowing it to efficiently cross cell membranes and replenish intracellular GSH levels. Once inside cells, it is rapidly hydrolyzed by esterases to release active glutathione. Glutathione ethyl ester is widely used in biomedical research to study oxidative stress, neuroprotection, liver health, and aging-related disorders. Its improved bioavailability over standard GSH makes it a valuable tool in antioxidant therapy, cellular protection studies, and metabolic health research.