For research use only. Not for therapeutic Use.
Gly-AMC, also known as L-Gly-7-Amino-4-Methylcoumarin, is a probe and chromphore substrate for aminopeptidase. it is useful to make the C-terminal conjugate of ubiquitin with 7-amino-4-methylcoumarin (Ub-AMC), which is an important probe for fluorescence-based anal. of deubiquitinating enzyme (DUB) activity.
Catalog Number | I028124 |
CAS Number | 208459-17-0 |
Synonyms | Gly-AMC HCl; H-Gly-AMC HCl; L-Gly-7-Amino-4-Methylcoumarin; H-Gly-AMC; ; ZINC57339; AK144290; DS-7861; DA-02879; FT-0698956; |
Molecular Formula | C12H13ClN2O3 |
Purity | 98% |
Solubility | Soluble in DMSO |
Appearance | Solid powder |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
IUPAC Name | Acetamide, 2-amino-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-, monohydrochloride |
InChI | InChI=1S/C12H12N2O3.ClH/c1-7-4-12(16)17-10-5-8(2-3-9(7)10)14-11(15)6-13;/h2-5H,6,13H2,1H3,(H,14,15);1H |
InChIKey | DGTMMNCLSKYGIF-UHFFFAOYSA-N |
SMILES | O=C(NC1=CC=C(C(O2)=C1)C(C)=CC2=O)CN.[H]Cl |