Gly-Pro-AMC hydrobromide

• CAT Number: M026417
• CAS Number: 115035-46-6
• Molecular Formula: C17H20BrN3O4
• Molecular Weight: 410.26
• Purity: ≥95%
• Synonyms: (2S)-1-(2-aminoacetyl)-N-(4-methyl-2-oxochromen-7-yl)pyrrolidine-2-carboxamide;hydrobromide
• InChI: InChI=1S/C17H19N3O4.BrH/c1-10-7-16(22)24-14-8-11(4-5-12(10)14)19-17(23)13-3-2-6-20(13)15(21)9-18;/h4-5,7-8,13H,2-3,6,9,18H2,1H3,(H,19,23);1H/t13-;/m0./s1
• InChIKey: PASXTQMFJRHMLJ-ZOWNYOTGSA-N
• SMILES: CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)[C@@H]3CCCN3C(=O)CN.Br

Gly-Pro-AMC hydrobromide（Cat No.:M026417）is a peptide substrate used primarily in biochemical research to study enzymatic activity, particularly for assessing the activity of proline-specific enzymes, such as prolyl endopeptidase. It consists of the dipeptide glycine-proline (Gly-Pro) linked to the fluorogenic group 7-amino-4-methylcoumarin (AMC). When cleaved by an enzyme, the AMC group is released, emitting fluorescence that can be measured. This property makes Gly-Pro-AMC hydrobromide useful in enzyme assays, drug screening, and studying protease activity, especially in research related to protein turnover, cell signaling, and disease mechanisms.